Immune profiling in human breast cancer is predictive of 5- and 10-year survival.
نویسندگان
چکیده
Conclusions Immune profiling of the TIL infiltrate in human breast carcinoma using high-sensitivity detection and analysis techniques showed predominance of CD3 cells, being ab-TCR, CD4 T cells of mainly memory phenotype. Importantly, these findings were strongly predictive of 5and 10-year survival. This indicates the real possibility that TIL infiltration in breast cancer might be open to immunological manipulation therapeutically to improve clinical outcome.
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015